Sterilants and high-level disinfectants


Formaldehyde – primarily available as a water-based solution called formalin, which contains 37% formaldehyde by weight – is used as a high-level disinfectant and sterilant. Formaldehyde exerts its bactericidal, tuberculocidal, fungicidal, veridical and sporicidal effects in the aqueous state, as well as in combination with low-temperature steam.The combination of peracetic acid and hydrogen peroxide has been used for disinfecting haemodialysers, but the mix was found to be incompatible with flexible gastrointestinal endoscopes as claimed by leading US manufacturers.  Peracetic acid acts as an environmental surface sterilant, and behaves similarly to other oxidising agents, disrupting cell wall permeability and oxidizing sulpha hydryl and sulphur bonds in proteins, enzymes and other metabolites.


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